Oruka Therapeutics Inc (ORKA) stock: 12-month forecast projects 74.43% potential return%

Nora Barnes

Oruka Therapeutics Inc [ORKA] stock prices are up 3.55% to $28.28 at the moment. In order to assess the stock’s recent performance, you can check whether its short-term value is rising or falling. The ORKA shares have gain 0.60% over the last week, with a monthly amount glided 25.05%, and seem to be holding up well over a long-time horizon.

From an analyst’s perspective:

Oruka Therapeutics Inc [NASDAQ: ORKA] stock has seen the most recent analyst activity on October 27, 2025, when Guggenheim initiated its Buy rating and assigned the stock a price target of $60. Previously, Barclays started tracking the stock with Overweight rating on October 13, 2025, and set its price target to $48. On May 22, 2025, BTIG Research initiated with a Buy rating and assigned a price target of $44 on the stock. Wolfe Research started tracking the stock assigning an Outperform rating and suggested a price target of $20 on February 04, 2025. Stifel initiated its recommendation with a Buy and recommended $49 as its price target on October 11, 2024. H.C. Wainwright started tracking with a Buy rating for this stock on October 07, 2024, and assigned it a price target of $45. In a note dated September 17, 2024, Leerink Partners initiated an Outperform rating and provided a target price of $44 on this stock.

The stock price of Oruka Therapeutics Inc [ORKA] has been fluctuating between $5.49 and $29.46 over the past year. Currently, Wall Street analysts expect the stock to reach $49.33 within the next 12 months. Oruka Therapeutics Inc [NASDAQ: ORKA] shares were valued at $28.28 at the most recent close of the market. An investor can expect a potential return of 74.43% based on the average ORKA price forecast.

Analyzing the ORKA fundamentals

To continue investigating profitability, this company’s Return on Assets is posted at -0.28, Equity is -0.28 and Total Capital is -0.33. Upon thorough examination of the company’s fundamental financial framework, it becomes apparent that the debt-to-equity ratio stands at 0.01.

Before buying any particular stock, readers tend to pay close attention to the indicators that support and create resistance. The company’s stock is currently sitting at 26.47 points at the first support level, and at 24.67 for the second support level. However, for the 1st resistance point, the stock is sitting at 29.86, and for the 2nd resistance point, it is at 31.45.

Ratios To Look Out For

It’s worth pointing out that Oruka Therapeutics Inc [NASDAQ:ORKA]’s Current Ratio is 27.42. In addition, the Quick Ratio stands at 27.42 and the Cash Ratio stands at 5.4.

Transactions by insiders

Recent insider trading involved Venrock Healthcare Capital Par, 10% Owner, that happened on Feb 14 ’25 when 88794.0 shares were purchased. 10% Owner, Venrock Healthcare Capital Par completed a deal on Feb 13 ’25 to buy 14950.0 shares. Meanwhile, 10% Owner Venrock Healthcare Capital Par bought 8971.0 shares on Feb 12 ’25.

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