This is why Vertex Pharmaceuticals, Inc (VRTX) Stock is one of the options for the Longer run

Nora Barnes

Vertex Pharmaceuticals, Inc [VRTX] stock prices are up 3.37% to $484.15 at the moment. Until recently, the best way to gauge how the stock has performed was to look at its short-term value. The VRTX shares have gain 6.70% over the last week, with a monthly amount glided 6.29%, and seem to be holding up well over a long-time horizon.

From an analyst’s perspective:

Previously, Wolfe Research upgraded its rating to Outperform on January 06, 2026, and kept the price target unchanged to $548. On December 03, 2025, upgrade upgraded it’s rating to Overweight but maintained its price target of $516 on the stock. Scotiabank started tracking the stock assigning a Sector Outperform rating and suggested a price target of $495 on November 13, 2025. Leerink Partners upgraded its rating to an Outperform but $456 remained the price target by the analyst firm on September 25, 2025. In a note dated August 06, 2025, Wells Fargo upgraded an Overweight rating on this stock but restated the target price of $460.

The stock price of Vertex Pharmaceuticals, Inc [VRTX] has been fluctuating between $362.50 and $519.68 over the past year. Currently, Wall Street analysts expect the stock to reach $488.1 within the next 12 months. Vertex Pharmaceuticals, Inc [NASDAQ: VRTX] shares were valued at $484.15 at the most recent close of the market. An investor can expect a potential return of 0.82% based on the average VRTX price forecast.

Analyzing the VRTX fundamentals

The Vertex Pharmaceuticals, Inc [NASDAQ:VRTX] reported sales of 11.73B for trailing twelve months, representing a surge of 12.27%. Gross Profit Margin for this corporation currently stands at 0.86% with Operating Profit Margin at 0.34%, Pretax Profit Margin comes in at 0.38%, and Net Profit Margin reading is 0.31%. To continue investigating profitability, this company’s Return on Assets is posted at 0.15, Equity is 0.22 and Total Capital is 0.2. An extended analysis of the company’s primary financial structure reveals a debt-to-equity ratio of0.11.

Before buying any particular stock, readers tend to pay close attention to the indicators that support and create resistance. The company’s stock is currently sitting at 471.90 points at the first support level, and at 459.64 for the second support level. However, for the 1st resistance point, the stock is sitting at 491.96, and for the 2nd resistance point, it is at 499.77.

Ratios To Look Out For

It’s worth pointing out that Vertex Pharmaceuticals, Inc [NASDAQ:VRTX]’s Current Ratio is 2.36. As well, the Quick Ratio is 2.00, while the Cash Ratio is 1.1. Considering the valuation of this stock, the price to sales ratio is 10.47, the price to book ratio is 7.10 and price to earnings (TTM) ratio is 34.12.

Transactions by insiders

Recent insider trading involved Tatsis Ourania, Officer, that happened on Jan 07 ’26 when 4500.0 shares were purchased. Officer, WAGNER CHARLES F JR completed a deal on Jan 06 ’26 to buy 9532.0 shares. Meanwhile, EVP, CO & FO WAGNER CHARLES F JR sold 14000.0 shares on Dec 03 ’25.

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