Sionna Therapeutics Inc [SION] stock prices are down -1.11% to $43.79 at the moment. Until recently, the best way to gauge how the stock has performed was to look at its short-term value. The SION shares have gain 14.01% over the last week, with a monthly amount glided 11.00%, and seem to be holding up well over a long-time horizon.
From an analyst’s perspective:
Sionna Therapeutics Inc [NASDAQ: SION] stock has seen the most recent analyst activity on November 19, 2025, when BTIG Research initiated its Buy rating and assigned the stock a price target of $50. Previously, RBC Capital Mkts started tracking the stock with Sector Perform rating on September 03, 2025, and set its price target to $22. On September 03, 2025, Raymond James initiated with a Strong Buy rating and assigned a price target of $45 on the stock. TD Cowen started tracking the stock assigning a Buy rating. Stifel initiated its recommendation with a Buy and recommended $32 as its price target on March 04, 2025. Guggenheim started tracking with a Buy rating for this stock on March 04, 2025, and assigned it a price target of $45.
The stock price of Sionna Therapeutics Inc [SION] has been fluctuating between $7.26 and $45.00 over the past year. Currently, Wall Street analysts expect the stock to reach $33.5 within the next 12 months. Sionna Therapeutics Inc [NASDAQ: SION] shares were valued at $43.79 at the most recent close of the market. An investor can expect a potential drop of -23.5% based on the average SION price forecast.
Analyzing the SION fundamentals
To continue investigating profitability, this company’s Return on Assets is posted at -0.17, Equity is -0.63 and Total Capital is -0.21. An extended analysis of the company’s primary financial structure reveals a debt-to-equity ratio of0.03.
Before buying any particular stock, readers tend to pay close attention to the indicators that support and create resistance. The company’s stock is currently sitting at 43.28 points at the first support level, and at 42.77 for the second support level. However, for the 1st resistance point, the stock is sitting at 44.55, and for the 2nd resistance point, it is at 45.31.
Ratios To Look Out For
It’s worth pointing out that Sionna Therapeutics Inc [NASDAQ:SION]’s Current Ratio is 25.61. As well, the Quick Ratio is 25.61, while the Cash Ratio is 5.43.
Transactions by insiders
Recent insider trading involved ORBIMED ADVISORS LLC, Director, that happened on Nov 24 ’25 when 94583.0 shares were sold. Director, ORBIMED ADVISORS LLC completed a deal on Nov 25 ’25 to sell 11890.0 shares. Meanwhile, Director ORBIMED ADVISORS LLC sold 1600.0 shares on Nov 26 ’25.
