Recent Performance of Spero Therapeutics Inc (SPRO)Stock: A Closer Look

A share price of Spero Therapeutics Inc [SPRO] is currently trading at $2.14, up 2.88%. Until recently, the best way to gauge how the stock has performed was to look at its short-term value. The SPRO shares have gain 8.08% over the last week, with a monthly amount glided 0.94%, and seem to be holding up well over a long-time horizon.

From an analyst’s perspective:

Spero Therapeutics Inc [NASDAQ: SPRO] stock has seen the most recent analyst activity on December 20, 2024, when Evercore ISI downgraded its rating to a In-line but kept the price target unchanged to $5 for it. Previously, Evercore ISI upgraded its rating to Outperform on September 23, 2022, and elevated its price target to $8. On October 01, 2021, downgrade downgraded it’s rating to Perform. H.C. Wainwright reiterated its Buy rating and increased its price target to $40 on January 22, 2021. Berenberg initiated its recommendation with a Buy and recommended $47 as its price target on December 16, 2020. In a note dated November 05, 2019, H.C. Wainwright reiterated a Buy rating on this stock and boosted its target price from $28 to $35.

Spero Therapeutics Inc experienced fluctuations in its stock price throughout the past year between $0.51 and $3.22. Spero Therapeutics Inc [NASDAQ: SPRO] shares were valued at $2.14 at the most recent close of the market.

Analyzing the SPRO fundamentals

Trailing Twelve Months sales for Spero Therapeutics Inc [NASDAQ:SPRO] were 34.09M which represents 96.14% growth. Gross Profit Margin for this corporation currently stands at 1.0% with Operating Profit Margin at -1.42%, Pretax Profit Margin comes in at -1.34%, and Net Profit Margin reading is -1.34%. To continue investigating profitability, this company’s Return on Assets is posted at -0.88, Equity is -1.22 and Total Capital is -1.22. An extended analysis of the company’s primary financial structure reveals a debt-to-equity ratio of0.11.

Before buying any particular stock, readers tend to pay close attention to the indicators that support and create resistance. The company’s stock is currently sitting at 2.07 points at the first support level, and at 2.00 for the second support level. However, for the 1st resistance point, the stock is sitting at 2.20, and for the 2nd resistance point, it is at 2.26.

Ratios To Look Out For

To put it in perspective, the Current Ratio for Spero Therapeutics Inc [NASDAQ:SPRO] is 3.97. As well, the Quick Ratio is 3.97, while the Cash Ratio is 2.09. Considering the valuation of this stock, the price to sales ratio is 3.53, the price to book ratio is 3.66.

Transactions by insiders

Recent insider trading involved Mahadevia Ankit, Director, that happened on Aug 28 ’25 when 6572.0 shares were sold. Chief Operating Officer, Keutzer Timothy completed a deal on Aug 28 ’25 to sell 1695.0 shares. Meanwhile, Chief Operating Officer Keutzer Timothy sold 56537.0 shares on Feb 05 ’25.

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