Are Annexon Inc (ANNX) stocks a prudent buy?

Kevin Freeman

Annexon Inc [ANNX] stock is trading at $5.53, up 8.43%. In order to assess the stock’s recent performance, you can check whether its short-term value is rising or falling. The ANNX shares have gain 9.72% over the last week, with a monthly amount glided 19.96%, and seem to be holding up well over a long-time horizon.

From an analyst’s perspective:

Annexon Inc [NASDAQ: ANNX] stock has seen the most recent analyst activity on December 23, 2025, when Chardan Capital Markets initiated its Buy rating and assigned the stock a price target of $16. Previously, JP Morgan upgraded its rating to Overweight on March 01, 2024, and kept the price target unchanged to $11. On December 21, 2023, upgrade upgraded it’s rating to Buy and revised its price target to $6 on the stock. Wells Fargo started tracking the stock assigning an Overweight rating and suggested a price target of $11 on October 30, 2023. BofA Securities downgraded its rating to a Neutral and reduced its price target to $3 on May 26, 2023. JP Morgan downgraded its rating to Neutral for this stock on May 25, 2023, and downed its price target to $9. In a note dated September 16, 2022, Jefferies initiated a Buy rating and provided a target price of $12 on this stock.

Annexon Inc [ANNX] stock has fluctuated between $1.28 and $5.48 over the past year. Currently, Wall Street analysts expect the stock to reach $16 within the next 12 months. Annexon Inc [NASDAQ: ANNX] shares were valued at $5.53 at the most recent close of the market. An investor can expect a potential return of 189.33% based on the average ANNX price forecast.

Analyzing the ANNX fundamentals

To continue investigating profitability, this company’s Return on Assets is posted at -0.9, Equity is -0.92 and Total Capital is -1.18. An extended analysis of the company’s primary financial structure reveals a debt-to-equity ratio of0.17.

Before buying any particular stock, readers tend to pay close attention to the indicators that support and create resistance. The company’s stock is currently sitting at 5.18 points at the first support level, and at 4.82 for the second support level. However, for the 1st resistance point, the stock is sitting at 5.81, and for the 2nd resistance point, it is at 6.08.

Ratios To Look Out For

For context, Annexon Inc’s Current Ratio is 4.42. In addition, the Quick Ratio stands at 4.42 and the Cash Ratio stands at 3.2.

Transactions by insiders

Recent insider trading involved Carson William H., Director, that happened on Dec 30 ’25 when 4115.0 shares were purchased. Director, Choi Jung completed a deal on Dec 01 ’25 to buy 33000.0 shares. Meanwhile, Director Carson William H. bought 4115.0 shares on Dec 01 ’25.

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