A share price of Upstream Bio Inc [UPB] is currently trading at $28.0, down -2.88%. In order to assess the stock’s recent performance, you can check whether its short-term value is rising or falling. The UPB shares have gain 12.27% over the last week, with a monthly amount glided 12.72%, and seem to be holding up well over a long-time horizon.
From an analyst’s perspective:
Upstream Bio Inc [NASDAQ: UPB] stock has seen the most recent analyst activity on November 18, 2025, when Evercore ISI initiated its Outperform rating and assigned the stock a price target of $40. Previously, Truist started tracking the stock with Buy rating on October 14, 2025, and set its price target to $47. On November 05, 2024, William Blair initiated with an Outperform rating. TD Cowen started tracking the stock assigning a Buy rating. Piper Sandler initiated its recommendation with an Overweight and recommended $75 as its price target on November 05, 2024. JP Morgan started tracking with an Overweight rating for this stock on November 05, 2024, and assigned it a price target of $38.
Upstream Bio Inc experienced fluctuations in its stock price throughout the past year between $5.14 and $29.29. Currently, Wall Street analysts expect the stock to reach $47 within the next 12 months. Upstream Bio Inc [NASDAQ: UPB] shares were valued at $28.0 at the most recent close of the market. An investor can expect a potential return of 67.86% based on the average UPB price forecast.
Analyzing the UPB fundamentals
Trailing Twelve Months sales for Upstream Bio Inc [NASDAQ:UPB] were 2.80M which represents 12.52% growth. Gross Profit Margin for this corporation currently stands at 1.0% with Operating Profit Margin at -44.65%, Pretax Profit Margin comes in at -38.37%, and Net Profit Margin reading is -38.37%. To continue investigating profitability, this company’s Return on Assets is posted at -0.25, Equity is -0.36 and Total Capital is -0.3. An extended analysis of the company’s primary financial structure reveals a debt-to-equity ratio of0.0.
Before buying any particular stock, readers tend to pay close attention to the indicators that support and create resistance. The company’s stock is currently sitting at 26.26 points at the first support level, and at 24.53 for the second support level. However, for the 1st resistance point, the stock is sitting at 31.37, and for the 2nd resistance point, it is at 34.74.
Ratios To Look Out For
To put it in perspective, the Current Ratio for Upstream Bio Inc [NASDAQ:UPB] is 32.67. In addition, the Quick Ratio stands at 32.67 and the Cash Ratio stands at 4.16. Considering the valuation of this stock, the price to sales ratio is 540.39, the price to book ratio is 3.99.
