At the time of writing, Upstream Bio Inc [UPB] stock is trading at $24.53, up 5.10%. One of the good ways to gauge the recent performance is if the stock’s short-term value is rising or falling. The UPB shares have gain 6.84% over the last week, with a monthly amount glided 10.10%, and seem to be holding up well over a long-time horizon.
From an analyst’s perspective:
Upstream Bio Inc [NASDAQ: UPB] stock has seen the most recent analyst activity on October 14, 2025, when Truist initiated its Buy rating and assigned the stock a price target of $47. On November 05, 2024, TD Cowen initiated with a Buy rating. Piper Sandler started tracking the stock assigning a Overweight rating and suggested a price target of $75 on November 05, 2024. JP Morgan initiated its recommendation with a Overweight and recommended $38 as its price target on November 05, 2024.
For the past year, the stock price of Upstream Bio Inc fluctuated between $5.14 and $26.90. Currently, Wall Street analysts expect the stock to reach $47 within the next 12 months. Upstream Bio Inc [NASDAQ: UPB] shares were valued at $24.53 at the most recent close of the market. An investor can expect a potential return of 91.6% based on the average UPB price forecast.
Analyzing the UPB fundamentals
According to Upstream Bio Inc [NASDAQ:UPB], the company’s sales were 2.80M for trailing twelve months, which represents an 12.52% jump. Gross Profit Margin for this corporation currently stands at 1.0% with Operating Profit Margin at -44.65%, Pretax Profit Margin comes in at -38.37%, and Net Profit Margin reading is -38.37%. To continue investigating profitability, this company’s Return on Assets is posted at -0.25, Equity is -0.36 and Total Capital is -0.3. An extended analysis of the company’s primary financial structure reveals a debt-to-equity ratio of0.0.
Before buying any particular stock, readers tend to pay close attention to the indicators that support and create resistance. The company’s stock is currently sitting at 23.33 points at the first support level, and at 22.12 for the second support level. However, for the 1st resistance point, the stock is sitting at 25.42, and for the 2nd resistance point, it is at 26.30.
Ratios To Look Out For
It is important to note that Upstream Bio Inc [NASDAQ:UPB] has a current ratio of 32.67. Also, the Quick Ratio is 32.67, while the Cash Ratio stands at 4.16. Considering the valuation of this stock, the price to sales ratio is 473.42, the price to book ratio is 3.50.






